Currently, the eighty or so members of the UNIS-UN Organizing Group are divided into seven commissions:
- Visiting Schools
- Editing
- Speakers & Debate
- Technology & Media
- Finance & Resources
- Public Relations & Logistics
- Ushering
Each commission is led by two to three junior or senior heads. Together, these commission heads form a coordinating team known as the Executive Committee (EXCOMM).
Preparations for the conference begin a year in advance, and include: finding and researching a contemporary global issue; selecting and inviting speakers; inviting several hundred students from national and international schools around the world and arranging for the majority of their accommodations with UNIS families; selecting students to partake in the conference Student Panel and Debate; and compiling a Working Paper of articles on the conference topic written by members of the UNIS-UN Organizing Committee and then edited by the UNIS-UN Editing Commission.